16 Patented Formulations


Lumiskin™ is a solution of diacetyl-boldine and caprylic/capric triglycerides that inhibit the activity of tyrosinase. It is used for its skin lightening properties. Diacetyl Boldine (DAB) works well via a-adrenergic antagonist receptors and calcium flow regulation. This product is recommended for use in skin lightening products. Lumiskin™ is recommended for use in emulsions, soaps and make-up products with lightening or whitening properties.


Pigmentation disorders are a big concern widely shared by most of the populations (Asian, African, Latin-American people). Amongst benign pigmentation disorders, some are stimulated by ageing (freckles, lentigines and melasma) and stress (inflammatory hyperpigmentation).

Sederma is proud to offer a new solution to people wishing to reduce irregularities in pigmentation or to lighten their skin complexion. Based on a botanical, Wonderlight™ acts on both melanocytes and their associated keratinocytes to help lessen pigmentation disorders. It regulates the Epidermal Melanin Unit cross-talking and blocks the signalling pathways involved in the melanin synthesis. Wonderlight™ exhibits a stronger effect on hyperpigmented areas and equalises skin pigmentation in order to make them less visible.

The ability of Wonderlight™ to inhibit the UV inducted secretion of GM-CSF (important melanocyte stimulator) was demonstrated in vitro. The concept was validated on living human skin cultures (phototype III) in which the UVAB induced the 2-fold increase in the number of melanocytes was totally inhibited in the presence of Wonderlight™.

Two clinical trials conducted on Asian volunteers with classical pigment disorders (lentigines, ephelides, melasma, post-inflammatory hyperpigmentation) confirmed the melanogenesis reducing the activity of Wonderlight™ on these lesions


Keratoline™ CPS is an enzymatic exfoliation that gently eliminates the dead cells to reveal younger, healthier looking skin. It is used in anti-age, slimming, whitening, peeling and scrubbing products. This product is based on a protease obtained by fermentation. Keratoline™ CPS is a gentle, enzymatic alternative to AHAs


RonaCare® Cyclopeptide-5 is the first homodetic cyclic peptide for cosmetic applications. Due to its smart design RonaCare® Cyclopeptide-5 provides high selectivity for its biological target – integrins at the RGD binding site. Tailor-made to fit certain skin cell surface receptors it mimics natural processes of skin communication and repair - unfolding its anti-ageing properties. The innovative cyclic molecular design paves the way to anti-ageing efficacy in a new dimension.

Crithmum Maritimum Callus Culture Filtrate

CELTOSOME™ Crithmum Maritimum ST is an exclusive Sea Fennel stem cell culture with specific skin lightening and wound healing properties. It helps inhibit all major steps of the melanogenesis process, regulate inflammation, increase cell renewal along with the synthesis of collagen, proteoglycans and glycosaminoglycans. The skin is smoother, more radiant and its tone evener. This all-natural ingredient in powder form is 100% active, solvent and preservative free, and compliant with Ecocert and Cosmos.

Pct Alp Rose

Alpine roses are typical Swiss flowers that grow at altitudes of 1500 – 3000 m. And it is in these distinct environments that they have to adapt to extreme conditions such as the cold, UV and dryness. PhytoCellTec™ Alp Rose is based on alpine rose stem cells and has succeeded in capturing these characteristics. PhytoCellTec™ Alp Rose helps to maintain the characteristics of skin stem cells and to protect these precious cells against UV-stress.

Pseudoalteromonas Ferment Extract

Pseudoalteromonas Ferment Extract is a strain of bacteria isolated from mud found on King George Island in Antarctica. It is a peptide that is classified as a protein derivative and contains the following three amino acid residues: glycine, histidine and lysine. It is used in a number of anti-ageing products because of its ability to regenerate and protect the skin by retaining moisture and water, heal wounds, increase collagen and elastin production, and improve hydration

Pearl Powder Extract

Pearl is a very special herbal substance used since ancient times. Powdered Pearl is used as a Shen tonicto stabilize the emotions, ease frustration and anger, brighten the eyes and help regenerate tissue! Pearl is also used as a major beauty tonic because it is believed that oral consumption of Pearl powder results in lustrous, pure, beautiful skin. Pearl powder is also used topically in skin creams to purify the skin. Pearls have a tremendous reputation in China as both a beauty tonic and as a Shen tonic


  • It offers various benefits related to your skin pertaining to sustainability, safety, quality and sourcing.
  • It boosts the skin’s ability to fight against pro-ageing agents and regenerate itself and protecting skin stem cells.
  • Resistem reduces micro-inflammations, redness, and complexion
  • Enhancing skin’s translucency and radiance.


  • Skin hydration
  • To replenish the natural lipids that are lost from exposure to harsh environmental factors, use of drying products, and during the ageing process
  • Restore moisture, fortify the skin’s natural barrier and help protect it against harm from foreign elements.
  • Ceramides are also particularly effective in treating eczema

Glycerin & Narcissus Tazetta Bulb Extract

  • Glycerin helps the skin to feel smoother and softer.
  • To facilitate moisture and defends against dryness
  • Helping to establish normal balance and hydration
  • Essentially, glycerin is a master at hydration and works best when combined with other replenishing and emollient ingredients.
  • Helps cell renewal and gives the skin a healthy appearance.
  • It also has soothing properties and helps to maintain the skin’s elasticity and brightness


Antarticine is a Glycoprotein from the Antarctic Sea. It aids with regenerating tissues and enabling faster healing of wounds. It also Increases collagen type I and IV, as well as elastin, resulting in a restructured skin and a reduction in wrinkles, especially on the forehead and around the eyes. Antarticine also helps the skin retain water, preventing dryness.


  • Synthetically derived peptide that is used in a wide range of skincare and makeup products.
  • It has water-binding properties and theoretical skin-restoring ability
  • It reduces the appearance of wrinkles brought on by repeated facial expressions
  • Commonly found in creams and serums to help regenerate skin cells.


Melaslow™ or more commonly known as the Satsuma is native to Japan. It was regarded as the fruit for perpetual youth and longevity as described in Kojiki and Nihon Shoki. It is rich in antioxidants and brighteners that help control melanin biosynthesis to help even out skin tone and control hyperpigmentation. Tyrosinase is the enzyme responsible for skin hyperpigmentation. Citrus Unshiu Extract effectively inhibited the activity of tyrosinase, thus prevents skin hyperpigmentation.

Palmitoyl Tripeptide - 5 

Improves collagen production and firms the skin by altering how skin cells function, It stimulates collagen production and healthy tissue growth. Highly effective to boost collagen production naturally.